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When an artery becomes damaged, the plaque is a means by which the artery is repaired. As your leg heals, the added tissues leave a scar. So, once a section of the artery becomes blocked with plaque, blood can no longer flow through the artery resulting in a heart attack or stroke.
A daily dose of aspirin reduces the risk of a heart attack in 75 percent of people with heart disease, but in about 25 percent of patients using it, aspirin offers no protection.